I'm not ambidextrous in most things, but I am with e-reader use. I tend to read lying on my back on the bed, holding up the Sony 505 (yes, I have to take it out of its case for this) and I switch hands as one gets tired holding it up. When I'm using just one hand (or sitting in a more conventional position) it's usually my left, as that's most convenient for the round page-turn button, but like ProfCrash, I'll still switch once in a while and use the buttons on the right instead, depending on the whole spouse, pet, tea, etc., situation.
This leads to an interesting thought: I'm planning to make leather reader covers and probably sell them on Etsy, once I've got my own done (does anyone have a round tuit I could borrow? I seem to need one). All of the book-style covers I've ever seen have opened on the right, like a western book. Would anyone (lefties?) be interested in one that opened on the left, like manga?
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