Disney World four days in March. Not a huge trip since we live only a 90 mile drive from it. We get a FL resident discount so get to go lots.
Road trip up the east coast to WV and MD in June for a week.
Maybe an impromptu cruise if some good last minute deals come up. If you can go on a few weeks notice or less they can be had for up to 75% off.
For Christmas this year, extended family heading down here where I will be hosting Christmas for 20+. Even the son-in-laws families will be coming. Looking forward to it.
2011 should be a great year.