I will go a step further and tell you the settings that will actually make PDFs that are a collection of scanner images look good and work well on the Reader. Get the pdflrf program mentioned above and use these settings:
The ones to take note of here, moving downward are:
1. Setting "Rotation" to 0.
2. Having "Join pages" turned off
3. Changing "Colors" from 4 to 8.
4. "Scale" can be changed depending on how you want the PDF to look, but to display a whole page the PDF on one page of the Reader, set it to "Fit to page" or "Fit to height."
I just noticed that I have "Stretch" turned on here, which fills out the screen with the PDF if you have "Fit to height" or "Fit to width" set. I think you'd get the same effect from just using the "Fit to page" setting, and it might even give a sharper image if it is actually stretching it out to fit the page after shrinking it down (I doubt it).
Anyway, like I said, these are the settings to use for a PDF that is a collection of images, such as a scanned book. For manuals/technical stuff with a lot of text, there are certainly some better settings to use, but you'll just have to mess around and find what works best. I am pretty sure that there are some command line versions of this program, and I'd actually appreciate it if somebody could post a quick explanation of how to use the settings I just described using the command line options. I mean, I could probably figure it out myself, but I'd bet that somebody else has already gone down that long road.
-Crustachio, Leader of the 35th Smoke of Montague