The 650 has a considerably better screen as it uses Pearl and doe snot have a touch layer. Also, the IR touch is a lot easier to use and a lot more accurate. Plus, without the touch layer, the screen does not show fingerprints nearly as much. There is less reflection and glare as well. The 650 is faster and has a better user interface. There is no reason not to get a 650 vs a 600.
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