1) Yes I do backup my books. While I've never lost a book from Amazon, I've lost books by other vendors because the books went out of print and this can happen to Amazon too.
2) The best was to remove multiple bookmarks is to open the book, use the menu to enter into "My Clippings & Notes" (something like that). Then all of you bookmarks and notes will show up. Select the bookmark and hit delete.
The other methods mentioned do work, but they are much more time consuming.
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