Most PDF file are sized for an A4 or US Letter sized page, and will therefore display very poorly on a 6" Kindle. The Kindle, almost uniquely amongst eBook readers, supports no form of PDF reflow; you have to "pan and zoom" to read a large page, which is painful in the extreme.
The Kindle DX, with its 9.7" screen, is a much better proposition for reading PDFs.
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