I do have a tag in Calibre for books I know are Canadian, but that's more the lit major in me who likes to sort and categorize
I do follow the awards, like the Giller and Booker, and some of those authors are Canadian but if the book does not interest me, the nationality of the author does not factor in.
I suppose the only way I am 'region-ist' is when I read an article on how Google or B&N or some other America-only company is going to be Number One and Win the Ebook War or some such nonsense, and then I laugh because the author of the article clearly does not realize how many non-American book customers there are and how ALL of them shop at other stores...