Tried reading the first Harry Potter when it came out and put it down 1/4 of the way through. Did not hold my interest at all.
Like other people have said, I tried reading Twilight and could not get past how poorly written it was. I have a friend at work who is 20+ years younger than I am and she is an avid sci-fi, adventure, horror and comic book reader and her take on the Twilight books were that they were written for teenage girls like a teenage girl would write a book. Given that I am neither a female or a teenager probably helps explain my lack of interest.