Calibre's output target devices include optimal image sizes for each selected device type. I don't know of any easy way to see a list of the sizes though. For the Hanlin V3 it is 560 x 730 and it is typically slightly smaller than the screen resolution (600 x 800 in this case).
For epub's I would use a large size, perhaps 768 x 1024, and the max_width CSS suggested by Jellby.
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