You can "zoom" to full page images on the Kindle 3, from the user's guide:
Quote:
Increasing the Size of a Picture
If you'd like to see a larger size of a picture or image you encounter in your reading material, simply follow these steps to zoom temporarily on the image.
1.Use the 5-way controller to position the cursor over the picture.
2.An image of a magnifying glass with a plus sign will appear on top of the picture.
3.Press the 5-way to zoom the image. You will see a expanded view of the picture that rotates if necessary to maximize the use of the display.
4.Press the 5-way (or any key or button, except the Home button) to return to your content.
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There is no zoom and pan though.
There is no way to zoom in K4PC, and Nook 4 PC and the other ePub Windows apps seem to be the same (no zoom unless fit to page is encoded into the ebook). There is zoom in Windows MobiPocket Reader, which is still one of the best Windows Reading apps.
Images used to be tiny, because ebooks were read on PDAs. They got a bit bigger when the Kindle became popular, but Amazon is now charging (some) publishers per MB downloaded - so images are not likely to get bigger. In general, ePubs tend to have larger images than Kindle ebooks but no ePub Reader I am aware of has user controllable image handling of any kind.