[ypocaramel]

Instapaper - there's some support with Cailbre, but an app would be better.
Evernote - just in case, I'm sure the Nook keyboard beats most smartphones' when I need to take notes in pinch.
Pulse - just an extension of the nook color's magazine abilities, Pulse is the way I enjoy rss, though it's no hardcore reader.
Dropbox and other methods of remote access to docs and pics. Hey, if it has quickoffice and wifi, this is just natural.
Apps that can highlight and annotate PDF and office docs with social networking like the default ePub program. Useful for students and academics.

Would also like to see a way to access iPad optimized versions of websites like gmail, it's more intuitive than desktop and more functional than mobile/phone.