If you are willing to lug around 4 lbs then the T2010 will certainly give you PDFs closer to full size than the iLiad. The other issue is eye strain, which is apparently caused by screen flicker (no flicker with E-Ink). The few PDFs I have tried were all readable on the iLiad, but I have not read PDFs for an extended period.
The iLiad is the most Zaurus-like of the existing e-book Readers, but the range of software available is still quite limited (e.g. much less than a Nokia 770 or 8X0). It is primarily a device for reading and note taking with some capability in other areas.
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