I'm also a lefty, and do most things lefty (except brush my teeth.....that one has always made me wonder, lol). I do use a right-handed mouse, but I think that's because the first computer we had in the house was shared by all the righties in the house, and I just learned to adjust (now trying to use it left-handed just feels weird). I've tried left handed scissors as a kid and HATED them....could never get them to work well, lol. And I've never, ever had any issues with using my kindle
