I would have to agree with most that if you're very un-tech-savvy and want the simplest all-around experience possible, I'd recommend the Kindle 3.
The only caveat would be if you want library books and/or to be able to buy outside of Amazon. In that case, I'd recommend Kobo (but I think a new one is coming out soon? so if you go with Kobo I'd recommend waiting for the new one).
I personally have a nook and love it, but it's slightly more complicated than the others (the touch screen). As ProfCrash said, B&N are announcing something today and it may be a new nook. The new nook may be simpler but we don't know just yet (we will in a few hours though).
You did mention arthritis and easy page turns though. With the nook (and I think Sony (?) and a few others), you can turn a page by swiping, meaning you don't have to press a button over and over, which could be a huge plus to you if pressing buttons hurts your arthritis. This could be a very important feature for you depending.
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