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Cavi, you make a good point about pixel density. When you can see the pixel structure (screen door effect), your brain is constantly trying to filter it out as you read the images on the screen. This leads to fatigue more than the high contrast or screen brightness. I would not want to read on an iPad for very long, however the iPod Touch 4 with the Retina screen is a joy to read on. The only disadvantage is the small screen size. I owned a Kindle DX, but returned it within the 30 day period because the lack of contrast and the gray background made it difficult to read without lots of ambient light. It was even to my surprise when I received the iPod Touch 4 that the pixel dense Retina screen actually provides a superior reading comfort to e-ink technology.
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