I'm currently using Bluefire Reader for DRM'd PDFs and ePubs in general (DRM'd and not). I'm using iAnnotate which I like rather better than Goodreader these days after the recent spate of improvements - both are really good but the tabbed access to open PDFs has me really favoring iAnnotate these days. I use Kindle for stuff that I can't get otherwise and it is really good as well with the new 2-column option in landscape mode. iBooks Txtr and Stanza have no benefits for me beyond the three apps above.
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