You can. There are various things to remove the DRM.
Assuming you are using Windows, the files will be in something like :-
C:\Documents and Settings\mhutch79_userid_on_that_pc\My Documents\My Kindle Content
You can download calibre, and grab the KindleForPc plugin that removes the DRM and install that.
Once that is done, import the book into calibre, export to epub/some other format, load to Nook.
There are other drm stripping and reformatting options as well. Searching mobileread will find you a few.
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