Sadly, there are no readers yet that are "best" for reading PDFs, especially. You will have to settle for some kind of compromise. Ideally, your reader should have a screen the same size as the original pages the PDF so the text will not require a magnifier to read. HYowever, depending on the size of the original book, that could require a large screen that isn't readily or inexpensively available. There are a few larger screened readers, such as the Kindle DX and LCD tablets, like the I-pad, but they are still a bit on the small side to get a full screen display unless the original page size was a paperback. They aren't all that portable, either.
An alternative would be to get a reader that has the same screen length as the width of the text, then read the page with the reader set to landscape. You would have to scroll down each page to finish reading it before moving to the next one. Not all readers do this or do it well. The older Astak Mentors add a margin in addition to the original book margin and will not zoom when viewing an image PDF making it pretty much useless for the purpose.
I've had good luck with the JetBook Lite. The zoom increases in large steps which means one could go from too small to too large in a single step. However, it also has a setting that sets the zoom to have the text to fill the width of the screen which usually works for me. I also like that it runs on easily replaced AA batteries. It's tempermental (I have to frequently reset it) but it's been the best I've found so far.
I would suggest putting a few PDFs of various sizes on an SD card and trying them out on store displays of various readers. You could also set up some "meet ups" via the first sticky thread in this forum to try out other kinds of readers not available locally.
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