woodygirl--
Not sure if this answers your question or not, but what I do is simply hook my nook up to my computer through the USB cable. Calibre then sees my nook and I can choose the books I want loaded onto my nook and choose "transfer to device" in Calibre's interface. The books are then transferred to the nook and show up in the "My documents" folder on the nook.
Hope this helps!
dordale