Since we finally have Sony readers officially in Australia, I bought both the PRS-350 and the PRS-650 for work and evaluated them for my own personal use, with some comparison to the iphone and ipad.
There are a few people here who have played with them longer and given more detail but here's a link to my review for those that are interested.
http://blog.haydon.id.au/2010/10/sonys-2010-readers-hit-australia.html
For those that want the executive summary, this is probably the first generation of e-ink devices that I've actually wanted to buy due to the touch interface, but as others have noted the lack of alternative fonts is a negative for what is now the premium e-ink device in the market.