It's been awhile since I used Windows, but creating a 2-up PDF shouldn't require any rocket science. Some great (free/open source) software you might want to know about anyway is
pdfcreator. This works as a virtual printer. You "print" to it from any application and it yields a PDF. If memory serves you can tell it how many pages of the output you want per page of the generated PDF. If you choose two, you'd get something like what appears in my screenshot. (You can also choose four or six, etc.) So you can create 2-ups from any application. (And if you already have a single-page PDF, you can print that PDF to PDFCreator to create a new 2-up one.)