Having now considered my above answer, and getting back to your question. I'd say as far as the moment to moment goes, if you know firstly your character's goal (what they want) it would then perhaps be helpful to see the plot as a series of stumbling blocks towards that goal.
In a murder mystery, for example, the detective has to find the murderer. His path is then a series of stumblings blocks: a second murder, a series of confusing clues, new revelations, twists and turns, all of them obfuscating him from reaching his goal.
Generally speaking, you shouldn't make it too easy for a character to have what they want. There ought to be things in his/her path, and at the end of the story, they're supposed to be changed by the journey they're gone through.
This is the way most popular fiction is written, though you can, in fact, do whatever you want.
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