Well, I downloaded a font management program and it only found one issue (a registry problem).
And windows really sucks with fonts (you can't just cut/paste fonts out of the windows/fonts dir).
For now, I just edited the C:\Program Files (x86)\Calibre2\fontconfig\fonts.conf and changed the path to the windows fonts and font cache dir and I can at least load Calibre now and play with it...
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