On the Sony PRS-505, with PRS+ installed, I can change the font of epub documents "on the fly". As long as the font isn't hard-coded in the epub document, I can create a style sheet for any font, as long as I upload the font to the reader. Currently I have dejavu, droid, fontin, gentium, helvetica, verdan and georgia fonts installed. I can switch between them any time I want. (Now if only I could choose more than three sizes.)
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