No, you certainly don't need to use "Connect" if you put the files directly on an SD card with a card reader. You would need it, though, if you wished to buy any books from the Connect Store.
Why not set up your system as dual boot 32bit/64bit? Best of both worlds, that way.
Nobody knows, AFAIK, if the CyBook has a 64-bit USB driver, but I wouldn't bet on it.
Do you have any compelling reason to use Vista 64? It seems to me to be more trouble than it's worth for a home system. Its only real benefits, as far as I can see, appear to be for applications such as very large databases where the removal of the 4GB process address space limit improves performance.
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