Yes, you can.
However, it does not use the Reader Library, but the new (and buggy) Reader for PC, which you can download at:
http://ebookstore.sony.com/download/
The new software is supposed to be an improvement - and the interface is prettier, plus it has some new features (such as syncing notes, highlights etc.). But it is a bit buggier than the old Reader Library (which wasn't the greatest software itself...).