I've played with both, and while I'm not really a fan of Amazon's proprietary stance, the Kindle gets my vote because it allows for synching of sideloaded books. I liked the touch screen plus page turn buttons on the Nook, but the touch screen isn't a deal maker/breaker for me. The page turn buttons are. Kindle "no-touch" (as I've been calling it) has the buttons and the whispersynch, so I'm currently planning on a Kindle for myself.
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