Is it a large image, i.e. bigger than your reader can display (590x775 for a Sony-505, I think)?
If so, do you have your calibre Output Profile correctly set to be SonyReader? (Preferences - Conversion - Common Options - Page Setup - Output Profile). This option makes sure that large images are scaled to a suitable size for your reader during conversion.
It's possible the "large blank space before and after the image" is actually an all-white part of the image itself.
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