Something on your computer is preventing calibre from accessing its own temporary files. Most
likely the permissions on your Temp folder are incorrect. Go to the folder
C:\\Users\\USERNAME\\AppData\\Local in Windows Explorer and then
right click on the Temp folder, select Properties and go to
the Security tab. Make sure that your user account has full control
for this folder.
Alternately, you can run calibre as Administrator, but doing so will cause
some functionality, such as drag and drop to not work.
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