Thank you for the suggestions. I did go through the cleartype tuning process, albeit to no avail.
I do not want to stress this issue too much, but I believe something must have changed in the E-book viewer as to how it handles font display a few versions back. This is not a problem or criticism, I only wanted to point out that it may not agree with certain systems.
I will update to SP3 at some point, but am apprehensive to risk current functionality in my netbook which is excellent.
E-book viewer worked so great up to recently!