In brief, a PDF file is designed for display on a certain sized 'page' - typically A4 or letter size for business office documents, or possibly 6x9 inches for a book. But one of my readers has a 5" screen (3x4), and the rest are 6" diagonal. None of the available PDF rendering software does a good job of zooming, panning, or cropping, and the programming required to try does use more power, than a simple mobi or epub file.
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