Rule #1: All DRM is evil.
Rule #2: Closed formats are always bad for the consumer.
So that rules out Acrobat, eReader, Microsoft Reader, Mobipocket Reader, iSilo, etc.
For eBooks, I stick with text/PalmDOC or RTF. Many of the eBooks I get are poorly edited (even the commercial eBooks that I buy) so I like to use WordSmith to correct them.
For web pages, nothing beats Plucker/Sunrise.
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