Genes, Chromosomes, and Disease: From Simple Traits, to Complex Traits, to Personalized Medicine by Nicholas Gillham is a nifty-looking overview of the history and issues surrounding exactly what it says in the title, free courtesy of publisher FT Press' Science series.
Currently free @
B&N and
Amazon UK (likely to drop in the
main store once Amazon gets that price-dropping glitch sorted out).
Description (frankendescription cobbled together from the e-book blurb and the "Back Cover" of the print version which was a bit more informative)
This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University.
The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.
This is an exceptionally readable overview of the rise and transformations of medical genetics throughout the past century. It thoroughly reviews the field, summarizes current scientific understanding, and encourages readers to seriously reflect on the ethical and social implications. Gillham explains
- How genetic diseases arise and why some ethnic groups are more susceptible to specific disorders
- How scientists are trying to identify the genetic factors underlying multifaceted conditions like diabetes and heart disease
- The value and limitations of genetic information in prevention, treatment, and cure
- The complex, subtle interrelationships between genes and cancer
- What science knows--and doesn’t know--about genetics and human behavior
- The fraught, controversial history of attempts to link genes with intelligence
- Gene therapy: what’s worked and what hasn’t
- The potential and profound implications of personalized medicine
Extensive references are provided, along with a complete glossary.