AFAIK, Sipix screens have a glass substrate just as eInk screens currently do, so there's no reason to suppose that they're more robust.
On the other hand, I really don't think that eInk screens ARE especially fragile. They are certainly not children's toys, and should be kept out of the hands of small children, but treat them with a reasonable degree of respect and there's no reason to expect problems. I've lost count of the number of different eInk devices I've owned, and I've never had a screen break. What breaks screens is not so much knocks, but twisting forces. Avoid those - and ALWAYS keep a reader in a decent case - and you should be absolutely fine.
Hopefully this year we'll finally see eInk screens with a plastic substrate. Goodness knows, they've been long enough in appearing!
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