Hi morbo3000. Welcome to the forum!
In calibre Preferences, Behavior - to the right is a list of formats. Check the one for PDF and any others you want calibre's reader to open. Which only happens if you select it in the booklist and view while in calibre.
If you're in the Mac OS and doubleclick a PDF file, that will open it in whatever application is set to open that kind of file, such as Preview. To change this in the OS, select the file, command i (for Get Info) and in the middle of the Info window you'll see "Open with:" next to a triangle. Click the triangle then select the application you want from the menu, such as Adobe Reader. There's also a choice for using this to open all files of this kind with that app all the time or just this once.
Last edited by unboggling; 07-29-2011 at 02:21 PM.
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