She should be able to register it. All she should need is an account on Amazon.com. But she would not be able to buy Kindle ebooks without a US credit card, so it might not be worth the bother.
There are other sources of ebooks. The Kindle can also read nonDRMed Mobipocket ebooks, which can be found at a number of places. If the Kindle owner is technically savvy, one could also buy ebooks in MSReader format, remove the DRM, and convert to Mobipocket format.
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