Well, I scanned two books tonight with your advice in mind. Worked really well.
The key is really making sure the borders are all gone. This can be minimized to some extent with the Plustek software, but as you move through a book (especially a hardback) the sides shift some so you're still going to need to do some trimming in Acrobat (I'm using 8). This is a bit easier with "Even only" and "Odd only' though many pages still need personal attention.
Still, HUGE help. Thanks again. It seems to be taking longer than it used to, but perhaps I'm just rusty.