I've never, fortunately, suffered from eyestrain or headaches from reading on a screen (CRT or LCD), but I find it much more comfortable to read on eInk than on a backlit display, not to mention battery life, heating, etc. Something that does trouble me, nevertheless, is reading on a backlit screen in an otherwise dark environment, I find it extremely annoying. An unlit screen forces me to turn on the light, which is a good thing
