I don't think so -- the bookmarks are stored in the cache.xml file on the Reader or memory card (depending on where the book in question is located). You might be able to manually add a bookmark to that file (provided you successfully mimic the format), but it would seem like more trouble than it's worth.
I have noticed that if I set a mark in the Connect Software before xfering to the Reader, the mark shows up on the Reader. That might be some help.
Peculiarly, you can't set a mark in a file that's already on the Reader via the Connect Software.
You
can xfer the book to the PC side, delete it from the Reader, set your mark and xfr it back to the Reader, but that's a lot of trouble.
I'm hoping they'll allow bookmarking files in the Reader via the Connect software at some point. Clearly the Connect software is a work in progress -- servicable, but not elegant.
