Unfortunately the metadata changes are not going to be imported into iTunes. Refer to
this thread which discusses the changes that Apple made with iTunes 10.6.3, disabling calibre's ability to add metadata to books sent to iTunes.
If you're using an older version of iTunes than 10.6.3, you can use the 'Connect to iTunes' feature, which will update the metadata to match when you send the book. If you're using 10.6.3, you'll have to make the metadata changes directly in iTunes.
G