The page turn buttons are on the left side of the 350, with guys hands they might be comfortably reached with the thumb of your right hand, but I am not sure about it.
I read mine all the time one handed and do the page turns with my right thumb. The direction of the swipe can be changed from <---- to ----> and it only take a few millimeters of motion.
It is the most wonderful little reader and with the dictionaries only a double tap away you will get much more out of your reading. Get one, you will love it.
And yes, it sounds petty.
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