Yes.
It's a bit clunky, but it can be done if you buy a PDF app.
If you just need to read (and not annotate) the 99 cent Goodreader App works great. You can hook up the iPad to your PC/Mac and drag and drop PDFs into Goodreaders File Sharing section in iTunes.
You can also download PDFs from the web browser into Goodreader by letting them load and then typing a "g" in front of the URL.
If you need to annotate, people here have had good things to say about iAnnotate, but I've not used it myself. I believe it is $6.99 currently, but will go up to $9.99 at some point.
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