Skipping the interceding debate and addressing your query - theducks mentioned ISBN import, which I believe is the only list-based method available, and which won't do you any good for non-isbn items.
The only thing I can think of is kicking that Excel spreadsheet over to Access, then googling for the needed code to export each record to a custom-named html file, which you can then add to calibre like a book, pulling the metadata from the file name.
This is NOT one of my areas at all - my Access use goes no further than using spreadsheets to create basic dbs so I can use the data more effectively and output simple reports. I just know that it's possible so I thought I'd mention it.
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