I'm inclined to believe that staring into a lightsource that refreshes itself constantly faster than your eye can catch it is somewhat more strenious for the eyes than reading e-ink.
I much prefer to use my e-ink device rather than my ipad to read. There's less glare and I need not be conscious about I hold the device to read optimally.
I've noticed a bit of "white knighting" from people having invested in a specific type device, can't we just agree that LCD readers have a huge advantage in being able to show colors, and e-ink devices might be more relaxing for your wee eyes?