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I have really bad eyes and what works best for me is paper or eInk in a reasonably well lit room. Clip on reading lights work so-so for me but still a bit better than backlit LCD/LED. Even with a backlit display I still need to be in a reasonably well lit room. My eyes fatigue faster with backlit displays. This is not empirical evidence as I'm sure that any testing has been done with people with far better eyesight than mine.
I am curious to see future improvements in display technology and hopefully my eyes will benefit.
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