The Boroda hack worked fine for my 350 - gives me my epubs in my preferred (free) Fontin font. Charis Sil is another good free one.
I've formatted my epubs in html in Word on my Macbook with Fontin at 10pt, line spacing at exactly 10.5pt (to spread them slightly) - then leave Calibre at defaults except for the margin setting which I reduce to 2pt.
Works great, and size is just right for me (making the ridiculously huge Sony small-to-medium font size jump irrelevant).
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