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adrian142 - it could be a conflict with OneDrive.
See ==>>
I am getting errors with my calibre library on a networked drive/NAS?
In this context cloud storage services are a network drive.
Either pause OneDrive before starting calibre components and resume it when you're done. Or use a stand alone folder and file synchronisation tool to update a copy of library on OneDrive from a local copy at a convenient time - WikiP has a long list of such tools.
BR