I can tell you categorically that page numbers would have no bearing on scientific texts. All of the major and most less major journals have offered both print and electronic formats for several years, miles ahead of commercial e-publication like we are using to read novels.
References are hyperlinked, and library databases, such as PubMed, also allow readers to surf on through the reference to the (often) full text being cited and (usually) at least the abstract of the cited material. Citing references is just a matter of cut-&-paste into a writing software package, such as End Note.
I think that would be a good model for e-book publications sometime in the future, after some format things are standardized better.