Here's my two cents: You should self publish both in multi-format DRM-free ebook format, and also via one of the POD publishers such as Wordclay or Lulu or CreateSpace. It's important to provide your book in both e- and p- formats because different readers want different formats, or some readers will want to own the book in both e- and p-.
Next, if the book truly is sellable, you might want to get an agent and give them a chance to sell your book for a big advance (most authors probably only get a $5-$10k advance, though that's more than the average self-published author makes. There are exceptions). If you do sell to a traditional publisher, make sure the rights to the book revert back to you if the publisher lets it go out of print. Also, you might want to negotiate retaining the e-rights to the book, though most publishers probably won't want to do that.
Today, I think most authors aspire to be traditionally published. Not to far in the future, I think this will flip around and more authors will begin aspiring to self-publish. More authors will realize that the bloom of the published rose soon fades once they learn how poorly most books, especially debut books, are handled by the publishers. I see a hint of that in your question, so kudos to you for your foresight.