Unless I missed it somewhere, the screen is not a touchscreen... for such a large device that could be used for PDF reading, the lack of a touchscreen for easy annotations is disappointing... at least, well, it would be a deal breaker for me.
I know I might be picky... but I love buttons for page turning, but for annotating I prefer a touch interface.
On the good side, I am really loving this trend towards larger e-readers. Hopefully, someone will build a really fully-accessorized (wifi, 3g, frontlit, touchscreen AND buttons) soon.
I can dream, can't I?